Classification of Amino Acid

Kamlesh Sahu

Classification - Amino acid classification according to reactive group or R group

  1. Aliphatic - Glycine, Alanine, Valine, Leucine, Isoleucine

  2. Aromatic - Phenylalanine, Tyrosine, Tryptophan

  3. OH- - Serine, Threonine

  4. Acidic - Aspartic Acid, Glutamic Acid

  5. Acid amide - Aspargine, Glutamine

  6. Basic - Arginine, Lysine, Histidine

  7. Sulphur - Cystine, Methionine

  8. Cyclic - Proline

take the front letters of amino acid names

  1. Aliphatic - GAVLI

  2. Aromatic - Phe, Ty, Try

  3. OH- - ST

  4. Acidic - Asp, Glu

  5. Acid amide - Aspargine, Glutamine

  6. Basic - Arg, Lys, His

  7. Sulphur - CM

  8. Cyclic - P

 

If you remember one letter code of amino acid than

  1. Aliphatic - GAVLI

  2. Aromatic - FYW

  3. OH- - ST

  4. Acidic - DE

  5. Acid amide - NQ

  6. Basic - RKH

  7. Sulphur - CM

  8. Cyclic - P

Symbolic representation after reduction of letters

 
  1. Ali

  2. Aro

  3. OH

  4. COOH

  5. CONH2

  6. NH2

  7. S

  8. Cyclic

GAVLI

FYW

ST

DE

NQ

RKH

CM

P

 


Classification - Dependent in the property of R group

  1. Non polar or Hydrophobic - Glycine, Alanine, Valine, Leucine, Isoleucine, Proline

  2. Polar uncharged - Phenylalanine, Tryptophane, Tyrosine

  3. Polar charged - Serine, Threonine (OH-), Cystine, Methionine (sulphur), Aspargine, Glutamine (acid amide)

  4. Positively charged - Aspartic Acid, Glutamic Acid

  5. Negatively charged - Arginine, Lysine, Histidine

Dependent in R group (Symbolic)

  1. Non polar or Hydrophobic - GAVLIP

  2. Polar uncharged - FWY

  3. Polar charged - ST (OH-), CM (S), NQ (acid amide)

  4. (+) charged - DE

  5. (-) charged - RKH


Classification - dependent according to polarity of R group.

Amino acid can be divided into the above 3 groups (non-polar, flexible and polar) and then subdivided by their chemical character.

Non-Polar -- 8 Amino Acids

Hydrocarbon        Ala Val Leu Ile Pro

Aromatic              Phe Trp

Thiol Ether            Met

Flexible -- 1 Amino Acids

Gly -- flexible because it has no side chain

Polar -- 11 Amino Acids

Alcohol        Ser Thr Tyr

Thiol            Cys

Amides        Asn Gln

Acids          Asp Glu

Bases          Lys Arg His


Practice many Times